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Re: Mirapex vs Requip vs Donstinex ?

Posted by SLS on July 11, 2005, at 21:17:06

In reply to Re: Mirapex vs Requip vs Donstinex ?, posted by Declan on July 11, 2005, at 15:07:25

Hi Declan.

Thanks for replying.

> Why do they (those other 2, anyway) cause somnolence?

The first thought that comes to mind is that postsynaptic receptors are downregulated and made less sensitive while presynaptic autoreceptors remain activated, preventing dopamine synthesis and release.

I really don't know. :-)


- Scott

 

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