Posted by temoigneur on June 8, 2005, at 20:51:32
In reply to Re: Anyone with Severe Anxiety/ mod Depression » temoigneur, posted by Mr.Scott on June 8, 2005, at 1:17:41
I'm deliberating over ketoconazole for reducing cortisol with prozac - the thing is on clomipramine my anxiety an OCD is gone - but I feel vegetative, buzzed on a low grade euphoria - so I'm looking into ketoconazole /w prozac - there's a european researcher who writes about two successful long-er term treatments with ket. augmentation - studies seem fairly sparse but one in the journal of clin. psychiatry suggested that ketoconazole may have a limited effect in treatment resistant depression. My GP says it makes complete sense - because she knows that cortisol levels are disrupted in depression... So I'm weighing the pro's and cons, and with invaluable help from Ed_UK, trying to find a safe way to approach this - it can cause liver damage - cirrohsis, hepatitis - hopefully rarely. Also, I wrote the manufacturer of mifepristone, and they do have a compassionate access program for low/no cost it's at:
Mifeprex is approved for ending early pregnancy and is not approved for any other treatments. Danco does have a compassionate use program for treatment of other diseases with mifepristone. This program is run by Dr. Beth Jordan at the Feminist Majority. You should contact her for more information and to see if your patient might be eligible for the compassionate use program. She can be reached by phone at 703-522-2214 or by email at bjordan@feminist.org. Corcept is also researching mifepristone for psychotic depression, and their contact information is as follows: 650-688-8800 general number and perhaps www.corcept.com or info@corcept.com.
poster:temoigneur
thread:507639
URL: http://www.dr-bob.org/babble/20050606/msgs/509814.html