Posted by darkhorse on May 12, 2005, at 6:29:36
In reply to Re: Not Really..., posted by krybrahaha78 on May 11, 2005, at 22:33:06
> Luvox was out in Europe way before prozac came out
Yes:
1- Fluvoxamine was introduced in 1983!!
2- Citalopram was introduced in Denmark in 1986
3- Fluoxetine in December 1987,then came the rest of the family.Regarding " selectivity" this is a propaganda!
For example :
Paroxetine affect NE,and AC in a moderate- potent
Sertraline affect DA and NE to a lesser extent.
Fluoxetine affect NE and 5ht2c.
Citalopram affect Histamine moderately.The only thing in common is that all affect 5ht potently, but in no way they are selective.
- Venlafaxine& Duloxetine also potently affect serotonin, but Venlafaxine is more like the others because it weakly affect NE.
- Clomipramine is the "Godfather" of all SSRIs, as it is a very potent SRI,but still is not selective
- Even Imipramine is more potent in serotonin than fluvoxamine and venlafaxine!!D.H.
poster:darkhorse
thread:496309
URL: http://www.dr-bob.org/babble/20050510/msgs/496774.html