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Clomipramine + prozac = HELP:!!

Posted by temoigneur on May 5, 2005, at 20:55:24

Hey all, in crisis here, I'm supposed to start full time summer study on Tues. and the med combo I'm on leaves me fairly drowsy, vegetative.

I was on 125mg Clomipramine - it worked well to control OCD - but numbed my mind, and dulled all ambition - the doctor added prozac - initially the first two days, it was activating, and although a little on edge I thought I might be alright.

I know that SSRI's can raise blood levels of TCA's. now on 20mg prozac, and 115mg clomipramine, I'm exhausted, sleep all day as if I was on 200mg clomipramine. My question is does anyone have any idea to what degree prozac may raise blood levels of clomipramine - maybe more importantly the active metabolites that are causing the sedation. Anyone with pharm experience have any suggetn on on how far back I should cut the clomipramine, to retain clinical gains, :) and get rid of sedation. Does anyone know on average how the prozac changes the clomp. prozac ratio, and on average how long this takes to reach stabilize.

Thanks so much. I don't have a pdoc right now, I asked if it would be good to get a blood level test, and track the level of clomipramine, but the consulting pdoc said no no, it's nothing to worry about, sometimes it can be a concern with luvox~:(

Ben


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poster:temoigneur thread:494252
URL: http://www.dr-bob.org/babble/20050504/msgs/494252.html