Posted by smith562 on April 9, 2005, at 7:20:01
In reply to Re: Never parnate with an SSRI » ixus, posted by smith562 on April 8, 2005, at 5:51:58
To Everyone,
I am extremely sorry to everyone following this post. Although I have heard of some patients getting selegiline and an SSRI for Parkinsons, the offical literature is that an SSRI and selegiline are *contraindicated*. Apparently there has been several case reports of serontonin syndrome with the combo of selegiline and SSRI or TCAs.
Once again, I am very sorry for posting misinformation. I am going to speak to more neurologists regarding this matter. I am going ask Dr Bob to consider removing/modifing the post.
Smith
> I know they are both non-hydrazine MAOIs and can be anxiogenic for some ... selegiline does metabolize to amphetamines. The problem with parnate was that I would never add an SSRI and risk serontonin syndrome/death. The data with selegiline at 10mg or below suggest it is fairly safe (thousands of parkinson's patients get selegiline and an ssri every year), although no guarentees.
>
> I am hoping low dose zoloft and klonopin will offset any anxiety induced by selegilne. Hopefully someone out there has maybe tried this and can give me feedback.
>
> Thanks Ixus! Hope you are well. Please keep the post coming!
>
> Smith
>
poster:smith562
thread:481264
URL: http://www.dr-bob.org/babble/20050408/msgs/481937.html