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Re: Seroquel Might Be Working

Posted by med_empowered on March 16, 2005, at 19:36:12

In reply to Seroquel Might Be Working, posted by TomG on March 16, 2005, at 16:45:42

hey! Glad you're feeling better! If you have a problem with med-induced hypomania/mania/mixed-episodes, you may want to be somewhat cautious with atypical antipsychotics. Strange, but true: it appears that some may induce hypomania/mania in some people. I've mostly heard about it re: Abilify, but, given the complex pharmacological properties of the atypicals, its worth monitoring. Some people will respond nicely to low/mini-dose antipsychotics and then lose the "oomph" as the dose is increased. The only thing I can compare it to is some studies with schizophrenics which found that sometimes mini-doses of both old and new antipsychotics work quite well on negative symptoms with minimal side-effects; as the dosage was increased to more "standard" levels, there was less of an effect on negative symptoms but more of one on positive symptoms; in addition, side-effects increased. If you're not actively suicidal, its certainly worth trying a mini-dose.


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