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Re: Cymbalta.. even when SSRI did not work?

Posted by med_empowered on March 2, 2005, at 6:44:42

In reply to Re: Cymbalta.. even when SSRI did not work? » Spriggy, posted by Phillipa on March 1, 2005, at 22:19:27

I tried it, and it was pretty good. *IF* it works for you, one major benefit is the dosing: lilly recommends that patients be treated and maintained on 60mgs. Its REALLY simple. But, there are other options...wellbutrin is an obvious one (totally bypasses serotonin, but may have its own problems)...Remeron (unique action seems to minimize a lot of the ssri weirdness some people get...that said, it can be really sedating and cause weight gain)...Tricyclics (obviously, heart weirdness, lowering seizure threshold, weight gain, and sedation problems; also watch out for mania and/or rarely, full-blown psychosis)...or combos. Some docs might also try stimulants (though docs are stingy about this, and seem to use ultra-low doses) or weird, little used anti-depressants like amoxapine (anti-depressant AND mild antipsychotic in one; used in psychotic depression, schizophrenia, and sometimes tough depression cases. IF it works, it seems to work quickly, but shouldn't be used for too long--risk of tardive dyskinesia.)


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