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Re: MAOIs prevent Parkinson's Disease?

Posted by linkadge on February 22, 2005, at 10:15:07

In reply to MAOIs prevent Parkinson's Disease?, posted by cubbybear on February 22, 2005, at 10:02:53

It's not really the extra dopamine that prevents the cells from dying. Ie taking cocaine certainly doesn't prevent parkinsons.

I believe it is something intrinsic about the way MAO-B inhibitors work, that makes them somewhat neuroprotective.

It's kind of still a grey area, but people aren't sure if deprenyl's antiparkinson action is due to MAO-B inhibition, antioxidant properties, or both.


So MAO-B inhibitors do have some neuroprotective properties. If this extends to mixed MAOA MAOB inhibitors is still unclear.

Parnate, could perhaps provide symptomatic relief, however.


Linkadge


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URL: http://www.dr-bob.org/babble/20050222/msgs/461727.html