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Interested in Nortriptyline... Side Effects?

Posted by cache-monkey on February 16, 2005, at 18:21:33

Hey all,

I'm in the process of a change in my med regime. Right now I have Klonopin at 1 mg/day for generalized and social anxiety. (I suspect I'll have to go a little higher, though to get that under control.) I'm just starting Lithium as a mood stabilizer, since there's a strong reason to believe that I have a "soft" BP.

I'd like to add on an anti-depressant. Ideally, this would help with attentional/motivational issues, anhedonia, and (most importantly) help me quit smoking; I've fallen into depression upon every recent quit attempt.

I've tried Wellbutrin before, but it ended up making me kind of more edgy in some ways. I'm thinking about low-dose selegiline, but all of the evidence on its effectiveness is based on somewhat small samples.

Nortriptyline has been suggested to me before on this board. I know it has clinical backing as an aid to smoking cessation, but would it be useful for attention/motivation/anhedonia?

Also, I'd like to know what the most prominent side effects are. (The info on RxList seems to take an everything-that's-ever-been-reported approach.) I'm especially interested in the effects on sexual function and weight.

Oh, and BTW I'm an intermediate CYP-2D6 metabolizer, which should increase the ratio of nortrip. to its metabolites, if this makes a difference for side effects.

Any information is greatly appreciated.

All the best,
cache-monkey


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poster:cache-monkey thread:458963
URL: http://www.dr-bob.org/babble/20050212/msgs/458963.html