Posted by Optimist on January 22, 2005, at 23:10:44
In reply to Re: Parnate/MAOi titration, posted by SLS on January 22, 2005, at 14:31:32
> Regarding the titration of Parnate, I think it first makes sense to decide beforehand what your initial target dosage should be. I recommend 40mg as the minimum. Start at 10mg. You should be able to go up 10mg every 3-4 days. You should certainly be up to 40mg by the end of week two. I would spend perhaps 3 weeks at that dosage to look for improvement. I don't think making an adjustment every three weeks is rushing things if no improvement is observed. It depends on your clinical response. If you begin to improve at a given dosage after 3 weeks, you can remain on it for perhaps another 3 weeks to see if the trend toward improvement continues. I guess this represents the ideal situation. If you are particularly sensitive to the hypotensive effects, you might have to slow down. You might want to begin thinking about how you will address insomnia of it should occur as a side effect. It is common.
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> Parnate is a good drug. I wish you well with it.
>
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> - ScottThanks for the info Scott. It helps to get all the info I can get since my pdoc doesn't seem to be very knowledgable with MAOi's.
I'm hoping insomnia won't be too much of a problem. I didn't have any problems on my Prozac/Wellbutrin/Adderall combo so I'm crossing my fingers. I regularily take my last dose of Wellbutrin before bed which doesn't seem to cause any problems either. I've heard of others having problems with that schedule. I know Parnate is notorious for causing insomnia though.
Thanks for the well wishing. :)
Brian
poster:Optimist
thread:445694
URL: http://www.dr-bob.org/babble/20050119/msgs/445998.html