Posted by lars1 on January 14, 2005, at 13:23:54
In reply to Re: Methamphetamine vs N-acetyl-l-cysteine » JayDee, posted by Larry Hoover on January 13, 2005, at 10:26:03
> One of the mechanisms by which methamphetamine does its damage is by inhibiting MAO. When combined with dopamine efflux induced by this drug, the inhibition of MAO leaves dopamine open to a multitude of auto-oxidative and enzyme catalyzed oxidative transformations.
Would it be safe to assume that since conventional MAO inhibitors like Nardil and Parnate don't cause dopamine efflux, they don't cause any of the dopaminergic damage that amphetamines do?
poster:lars1
thread:439943
URL: http://www.dr-bob.org/babble/20050113/msgs/442143.html