Posted by Ritch on January 10, 2005, at 9:59:35
In reply to Re: Klonopin/Depression,why?, posted by darkhorse on January 10, 2005, at 8:57:45
> > I've taken clonazepam for more than 18 months straight. Starting at 1mg per day, now down to .25mg, because I find that low dose to be effective.
> > Zero problems whatsoever, only a good therapeutic effect.
> > I think there may be a "type" of person, and/or versions of mood disorders, that experience a depression response from benzo's, just as there are for other medications -including seemingly "common/simple" drugs, like acetaminophen and caffeine.
> > Sometimes, I think the response is psychological...the anxiety is the most acute or over-riding symptom, and once that has been removed by the benzo, the underlying depression is then revealed. The constant adrenaline of anxiety & stress also drives and energizes.
> > That's worth considering.
> > If you notice a correlation of bad s/e's to a drug or supplement........stop taking it!!! There are always alternatives.
> > Take care, all.
> > Jas
>
>
> I took lots and lots of different benzos (Ativan,Xanax,Valium,Frisium,Tranxene,Prazepam,Cloxazolam,Oxazepam,Rohyponol,Lormetazepam,and many many more)and Clonazepam was the only benzo that always gave from the first pill,no matter what the dose is, a blue feeling,helplessness,depressive thoughts....most benzos give depressive symptoms during withdrawal from medium - long use.....but nothing like clonazepam which has this severe symptoms while on the drug and after.........
>
> I noticed from some readings that clonazepam,unlike all other benzos, has some unknown serotonergic effects,and I suspect that it has to do with what lots of people experience as depression from clonazepam.
>
> Just my experience and some thoughts about the cause...
>
> Any I deas and input about Klon&depression?
>
> Dark Horse
>
>
Don't know the particulars.. but I think clonazepam is supposed to be a modest "releaser" of serotonin-a property the other benzos are supposed to lack, also I think it does something a little "extra" at the BZD receptors the others don't (not sure here though). Another thing.. I don't like to take any clon in the daytime if I can avoid it precisely because of the mild depressogenic effects. If I'm panicky that's different for reasons similar to the above statements, but I don't take benzo just for pure anticipatory anxiety. There's something else too-it seems the first four or five hours after taking a dose (in the daytime), I notice that blue feeling you speak of.. but about six hours in I feel a definite improvement that lasts for several more hours-I wonder if there are metabolites that affect mood differently from the parent compound.. or secondary effects that take a few hours (maybe the serotonergic ones)?
poster:Ritch
thread:438523
URL: http://www.dr-bob.org/babble/20050108/msgs/440082.html