Posted by King Vultan on December 19, 2004, at 0:55:40
In reply to Starting Nardil... dosage concerns, posted by jclint on December 18, 2004, at 9:19:58
My pdoc has over 20 years of experience with Nardil, and I believe the dosing regimen he had me follow is pretty close to what's in the PDR. I started on 3 x 15 mg/day for a week or two to see if I could tolerate it, then met with him again before going up to 4 x 15 mg/day, which seems to be considered more or less the minimum effective dose. In my case, the 45 mg/day had no adverse or therapeutic effects, 60 mg/day had mainly adverse effects (insomnia), and it wasn't until I got up to 75 mg/day that I got a noticeable antidepressant effect.
As I've mentioned many times before, there is one school of thought on Nardil that a person needs to get to 1 mg/kg body mass/day to be sure that they are giving the drug a fair trial. In my case, at about 68 kg (150#), this did correlate, as I did not notice substantial therapeutic effects until I got to 75 mg/day. As I said, it is just one school of thought on the drug and may or may not stand up to rigorous analysis; my pdoc said he had not actually heard of it.
Todd
poster:King Vultan
thread:431177
URL: http://www.dr-bob.org/babble/20041217/msgs/431527.html