Posted by ed_uk on December 12, 2004, at 8:08:15
In reply to Re: need you experiences with aurorix/manerix, posted by tensor on December 12, 2004, at 7:52:25
Hi Mattias,
I knew I'd read something about moclobemide and Finland. From psycho-pharmacology tips.....
Date: Wed, 31 Jan 1996 15:57:11 +0200 (EET)
From: Pekka Roponen <shrink@walrus.megabaud.fi>
Subject: Experience with moclobemideMoclobemide is the most frequently prescribed antidepressant in psychiatric practice in Finland. According to a Finnish double-blind multicenter trial, it was as good as or better than fluoxetine in all aspects when treating major depression (DSM-III-R criteria). Moclobemide was better in patients with atypical features.
According to my judgement moclobemide is the drug of choice in major depression because it does not cause EPS or any other major side effects. Not all patients are helped by it, of course.
Moclobemide is routinely prescribed here in combination with heterocyclic antidepressants (not clomipramine). There is no reason to anticipate any special side effects. I myself combine it with trimipramine or maprotiline to induce nighttime sedation. But the combination with SSRI-type drugs is dangerous -- small overdoses combined can lead to fatal serotonin syndrome.
I think that moclobemide is probably worth a try even though many people on babble have a low opinion of its efficacy. Personally, I took moclobemide after Effexor. My washout period was three weeks. This was longer than is recommended but my pdoc wanted to be extra careful.Regards,
Ed.
poster:ed_uk
thread:428123
URL: http://www.dr-bob.org/babble/20041211/msgs/428169.html