Posted by SLS on December 3, 2004, at 9:41:12
In reply to Re: why not dopamine for depression?, posted by Sleepless in the ATL on December 1, 2004, at 7:44:44
My gut feeling is that dopaminergic limbic and prefrontal pathways represent circuits that are downstream and secondary from the primary pathology. As such, agents that target these pathways exclusively are more palliative than corrective. Perhaps this is why psychostimulants and DA receptor agonist usually produce incomplete and short-lived antidepressant effects.
- Scott
poster:SLS
thread:413480
URL: http://www.dr-bob.org/babble/20041201/msgs/423833.html