Posted by Keith Talent on November 13, 2004, at 22:49:50
In reply to Looking for similar withdrawal experiences..., posted by tom_traubert on November 10, 2004, at 20:03:28
I experienced a dysphoric hypomanic episode upon discontinuing amitriptyline. Clomipramine might be expected to be worse, as it is more potent at blocking serotonin reuptake and its metabolite desmethylclomipramine is stronger at blocking noradrenaline reuptake, than amitriptyline. I take clomipramine now and find it better than any other antidepressant. There seems to be no problem starting at high doses, but there is a problem stopping - a slow taper is necessary.
poster:Keith Talent
thread:414392
URL: http://www.dr-bob.org/babble/20041113/msgs/415651.html