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Re: Pregabalin (Lyrica) for Social Phobia

Posted by SLS on November 7, 2004, at 7:24:28

In reply to Re: Pregabalin (Lyrica) for Social Phobia, posted by ed_uk on November 7, 2004, at 6:36:38

> The study should definately help... I think a lot of people will be printing it out!
> Ed


I don't know enough about the rating scale to judge the absolute efficacy of pregabalin in this study, but at first look, the results seem disappointing. The placebo response was very high. At a dosage necessary to differ significantly from placebo, side effects became very prominent, with 23% withdrawing from the study.


Side Effect % - Placebo/150mg/600mg

Somnolence - 9 10 43
Dizziness - 9 12 40
Headache - 24 29 21
Abnormal thinking - 7 2 21
Asthenia - 7 14 19
Nervousness - 9 0 13
Amblyopia - 0 2 11
Amnesia - 4 2 11
Depersonalisation - 0 5 9
Incoordination - 0 0 9
Insomnia - 13 7 9
Decreased libido - 0 0 9
Nausea - 4 7 9
Withdrew due to adverse events - 9 10 23

 

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poster:SLS thread:412679
URL: http://www.dr-bob.org/babble/20041103/msgs/412796.html