Re: is depression more about dopamine or serotonin?

Posted by linkadge on October 29, 2004, at 11:00:28

In reply to is depression more about dopamine or serotonin?, posted by lostforwards on October 29, 2004, at 10:37:56

I think there are different subtypes of depression that respond to different treatements.
Anergenic and anhedonic individuals probably have low dopamine. However pessemistic anxious insomniacs probably respond to the inhibitory actions of the SSRIs. Depression is supposedly related to lower levels of growth factors in the hippocampus. SSRI's enhance neurogenesis as do most effective antidepressants.
Statistically, ECT, the most effective antidepressant, has strong effects on serotonin neurotransmission as well as dopamine.
So is dopamine, more involved than serotonin ?, I think it depends on the person.
I was angry and irritable on ritalin, but calmer and happier on celexa. For some, it is the opposite.

Linkadge

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is depression more about dopamine or serotonin? lostforwards 10/29/04
Re: is depression more about dopamine or serotonin? linkadge 10/29/04
Re: is depression more about dopamine or serotonin? sabre 10/29/04
Re: is depression more about dopamine or serotonin? Sebastian 10/30/04
Re: is depression more about dopamine or serotonin? linkadge 10/31/04

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