Posted by yznhymer on October 17, 2004, at 15:22:31
In reply to Re: Cymbalta (duloxetine) - report, posted by yznhymer on October 15, 2004, at 17:50:33
> I believe this is day 12 on Cymbalta 30 mg for me and its not going all that well. The side effects are very uncomfortable. I feel very anxious and shaky as well as very sleepy. Yet, there is no rest in sleep. I took two ativan last night and managed 4 hours of continuous sleep. I am exhausted today, again.
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> My libido has disappeared as well as my ability to do anything in that department even if I were so inclined. I have no appetite and have lost about 9 pounds. That is the one bright spot for me at this time. This misery might be worth the weight loss but otherwise I have become almost non-functional. I have become so irritable that I'm afraid I might snap someone's head off under the right circumstances.
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> I'd forgotten what misery these trials can be and remember now why I've lost hope in a medical solution to my depression.
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> MarkHey Mark...
Day 14 on Cymbalta and the side effects noted above continue. Yesterday I went to a barbecue in Golden Gate Park. The anxiety I experienced was physically palpable and I was sleepy the whole time. I went home for a nap before the evening I had planned but was unable to relax enough to sleep. I just could not lay still. At dinner with friends in a groovy french bistro the discomfort continued. I kept getting hot flashes and the sweat was dripping down the back of my neck. I enjoyed splitting an appetizer with a friend but could barely eat my main course. Later, in the theater, the pressure in my chest and the other symptoms of anxiety were so uncomfortable that I had to leave at intermission. I slept on and off through the night and well into the morning.
Anyway, I'm wondering what about this drug drives my anxiety so high? Is it the serotonin or the norepinephrin action, or both? I've had similar experiences with other SSRIs. It seems to me there ought to be a more informed way to choose meds to try rather than just hit or miss. I don't know where to go from here. I'm feeling a bit better this morning but can't bring myself to take todays dose of Cymbalta. On the other hand I don't think 2 weeks makes for an adequate trial. I guess I'm taking a break from meds today but don't know what to do tomorrow.
Mark
poster:yznhymer
thread:380308
URL: http://www.dr-bob.org/babble/20041012/msgs/404180.html