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Re: SLS - memantine » SLS

Posted by Emme on September 19, 2004, at 15:33:24

In reply to Re: SLS - memantine, posted by SLS on September 19, 2004, at 14:41:28

Hi Scott,

> I am currently taking:
>
> Cymbalta 60mg
> Lamictal 150mg
> memantine 20mg
> Abilify 10mg

Interesting combo. I found abilify faded on me and the restlessness and sleep interruption got annoying. Sometimes I think about restarting it for a while to see if I can get back some of the initial great effects.

> I experienced an antidepressant response to memantine during my second week of treatment. It lasted for a few days and then faded. The response was pretty comprehensive in scope, although limited in magnitude. Energy, motivation, concentration, and mood were all improved. None of that improvement remains, however, I continue taking it in the hopes that it might act as an augmentor to Cymbalta by modulating neuroplasticity.

That is too bad that it never produced a more robust and sustained response.

> I'm sorry your treatment with Mirapex didn't provide you with the results you were looking for. To tell you the truth, I haven't seen a single person continue with it beyond a few months.

Yeah, the mood improvement was a plus, but I need to not feel like a zombie or my mood will plummet just from getting nothing done. I'm not feeling optimistic about this drug anymore. But it occurred to me that maybe I actually need to increase the dose. The 0.062 mg I'm taking isn't a lot. Maybe a few days at a higher dose would settle the question one way or the other.

> Perhaps you could keep a mood chart. I have one on my website you can use. Let's see if this URL works:

It looks like a good mood chart. For the past few years I've kept calendars - the kind with white squares to write things in. Maybe I'll try yours too.

> Let me know if there are any other questions I can answer for you. I think memantine is worth a try. That I responded to it at all is amazing.

Thanks. I'm going to keep memantine on the list of things to try and mention it to my pdoc this week. Have you noticed much in the way of side effects from it?

Emme

 

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