Posted by chemist on August 22, 2004, at 23:10:51
In reply to Re: the generic thing? » chemist, posted by Fred23 on August 22, 2004, at 22:35:44
hello again, chemist here....thank you for clarifying. the generics have, in all cases where the medication is in tablet form and all capsules except one (i will get to some caveats in a moment), been of equal efficacy in my experience with the following (as generics and name brand, various generic manufacturers, but usually watson, teva, geneva, purepac, mallincrodt, INC, barr): xanax, klonopin, valium, ativan, halcion, luvox, dalmane, restoril, and dexedrine. parnate was available to me as brand name, as were neurontin, gabitril, topamax, and trileptal, at the time: i cannot comment on any of these that are now available in generic formulations, and am not sure if any are off-patent yet. the one delayed onset incident was with a trial of dextroamphetamine sulfate ER in 15 mg capsules, made by mallinckrodt: i had been taking the name-brand 5 mg tablets, and the alternative was not to my liking. this could be due to the extended-release aspect (vs. the immediate release i was used to), and nothing else: i cannot say. i currently use the generic 5 mg dextroamphetamine sulfate tablets from Barr (immediate release), and they are just fine. aside from our own experiences, i am curious about those of others: i know of one individual who has received what is likely a mix of older tablets + fresher ones, and there is real variability in what are seemingly identical generic 1 mg xanax tablets. however, bioequivalence is rarely a problem with tablet formulations, somewhat more with capsules, and pronounced with creams/gels/ointments, as the trnasdermal delivery systems are done on the cheap, and the brand-name Retin A (johnson and johnson) is superior to at least a couple of generics, for example. apologizes for the gruff demeanor, i am curious about this phenomena, as it seems quite rare....all the best, chemist
> > hello there, chemist here...on the off chance that the repeated and erroneous *opinions* concerning generic formulations of an entire class of drugs commonly used by visitors to this board are responsible for numerous and potentially dangerous side-effects, i invite any poster who has any hard evidence at hand to provide it, and do so in short time. generic drugs of the benzodiazepine/triazolo-derivative class are rated with a T.E. of no less than AB in every case by the United States Food and Drug Administration: the information contained in the IND/NDAs for the various compounds are the references i cite in contesting this recurring and patently false claim. if a person chooses to waste their money as indicated in the post i am responding to, that is their choice. unlike some folks, i would like to see some independent results - such as literature, peer-reviewed, and not funded by any pharmaceutical concern - or well-controlled (with placebo), double-blind, randomized trials with a sufficient cohort - before spending exorbitant amounts of money based on one individual's claim. i look forward to the receipt of the requested information: please do post it publicly and prominantly, as it will be of service to the estimated 2 million + visitors to this site each month. thank you, and all the best, chemist
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> I've cited my personal experience with Ativan several times here, and have heard from others with similar experiences.
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> (You were offering me advice in my "sounding out the idea" stage. But you didn't seem to comment when I reported a dramatic difference between the generic and the name brand. In other words, I personally experienced the difference. Many others here had simliar experiences, though many also found the generic to be OK.)
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> I'm aware that this is a controversial issue, but many people have reported here that in certain cases, name brand medications really do work better than the generic.
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> I'd be curious about your personal experience with all the benzos you'be been though, have the generics truly done as well as name brand?
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poster:chemist
thread:380672
URL: http://www.dr-bob.org/babble/20040821/msgs/381093.html