Re: is nardil more selective to MAO-A

Posted by King Vultan on April 20, 2004, at 12:10:48

In reply to is nardil more selective to MAO-A, posted by linkadge on April 20, 2004, at 7:47:44

I'm not really sure if that's the case, or if it's just that Parnate is more pro-dopaminergic in comparison. The tranylcypromine molecule is very similar in structure to that of amphetamine and does have a direct stimulant effect; although, it is certainly not as powerful as amphetamine is. Still, it seems likely that this is the reason that Parnate is skewed towards dopamine, anyway.
Perhaps, then, Nardil might be an example of a "pure" MAOI, with serotonergic effects just naturally dominating those that are dopaminergic. I'd be interested in hearing from anyone more familiar with Nardil's pharmacology, though, and whether its traditional characterization as being nonselective deserves further elaboration.
Todd

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is nardil more selective to MAO-A linkadge 4/20/04
Re: is nardil more selective to MAO-A SLS 4/20/04
Re: is nardil more selective to MAO-A King Vultan 4/20/04
Re: is nardil more selective to MAO-A SLS 4/20/04
will nardil make my heart race linkadge 4/20/04
Re: will nardil make my heart race djmmm 4/20/04
Re: will nardil make my heart race » linkadge luther 4/21/04
Re: will nardil make my heart race King Vultan 4/21/04

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