Posted by scott-d-o on January 7, 2004, at 23:06:11
In reply to Amisulpride, posted by falconman on January 7, 2004, at 6:28:26
> Hi,
> I've been on amisulpride 100mg for social phobia/depression now for 4 weeks. I don't think its working at all. Still emotionally very flat. Anyone got some advice? Is it worth dropping dose to 50/75mg?
> ThanksI would say it is worth a try, in fact I would probably recommend having started at 50mg/day to being with; this is the dosage most people seem to have success with for depression. It seems people with dysthymic depression respond better with amisulpride as opposed to endogenous/major depression. Does the following sound like you:
Habitually gloomy, pessimistic, humorless, or incapable of fun; passive and lethargic; introverted; skeptical, hypercritical, or complaining; self-critical, self-reproaching, and self-derogatory; and preoccupied with inadequacy, failure, and negative events.
Another option is to try augmenting amisulpride with a medication that blocks dopamine reuptake. Examples are amphetamines, Wellbutrin, Ritalin, etc. I found a combination of sulpiride and Wellbutrin works wonders for my dysthymia/ADD. My current meds are Klonopin, Wellbutrin and sulpiride for social phobia, inattentive ADD, and dysthymia.
If this still doesn't help I would look at meds besides dopaminergic ones. I assume you have already been through some of the SSRI meds? What about tricyclics or Effexor?
scott
poster:scott-d-o
thread:297519
URL: http://www.dr-bob.org/babble/20040105/msgs/297898.html