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Re: Mefipristone vs. ketoconazole for high cortisol

Posted by SLS on December 13, 2003, at 8:08:24

In reply to Mefipristone vs. ketoconazole for high cortisol , posted by dannen on December 12, 2003, at 17:52:46

There are several ongoing trials using mifepristone (RU-486) to treat depression that are being funded by the NIMH. One trial found it to work well for psychotic depression. I don't remember where I read it, but it was stated that mifepristone was administered acutely for a short period of time upon which the depression resolved. The drug was then discontinued, and the antidepressant effect persisted long afterwards. I think the idea is to force the HPA to reset itself to a more normal state.

Are you considering trying it?

- Scott

 

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URL: http://www.dr-bob.org/babble/20031213/msgs/289338.html