Posted by rod on August 28, 2003, at 21:54:02
I looked at Dr. Amens website www.brainplace.com
He is saying, that people with temporal lobe hypo/hyper perfusion, often get significantly worse on serotonergic drugs like the SSRIs. (I do)http://www.brainplace.com/bp/atlas/ch7.asp
"...Decreased prefrontal cortex activity with increased or decreased temporal lobe activity. ... We have seen this subtype often made significantly worse by serotonergic medications and it is often helped by anticonvulsants, such as gabapentin or divalproate. ..."There are 2 case reports with this "subtype". They were helped with Lamictal and Tegretol. huh? Wasnt he talking about the GABAergic drugs like gabapentin or divalproate. Tegretol works a little on GABA, but Lamictal does quite nothing on GABA. Furthermore I could not find any study at pubmed, confirming his "findings" about temporal hypo/hyper perfusion and drugs such as gabapentin or divalproate.
Does anybody know more about this?? Has anyone an article/study which confirms this? (Or at least mention something like that)
I am asking, because I get my results of a HMPAO-Spect (brain perfusion) tomorrow and would like to have more drug related options, if I fit his criteria for the 3rd subtype (Decreased prefrontal cortex activity with increased or decreased temporal lobe activity)
thank you
Roland
poster:rod
thread:255193
URL: http://www.dr-bob.org/babble/20030828/msgs/255193.html