Posted by Larry Hoover on August 6, 2003, at 17:53:57
In reply to Re: musings about my experience with Enada NADH » Larry Hoover, posted by DSCH on August 6, 2003, at 16:02:08
> Larry,
>
> Have you tried time-released vitamin B complex supplements before?I generally use a time-release. They cost about the same.
> And if so, and NADH is superior, what do you think could be going wrong with the body activating B3?
I can only speculate. The most common forms of supplemental B-vitamins are not active. They must be modified by enzymes to make them useful to the body.
In my own case, it seems obvious that something is awry in the activation process for B-3, whether a literal defect or bottleneck affecting rate.
One of the central roles of NADH is the formation of adenosine triphosphate (ATP), more or less the universal cellular energy storehouse. It would be ironic if ATP is required by the enzyme that activates B3 to NADH, would it not?
> Have you tried B6 and/or its active co-enzyme PLP or P5P?
I have never used the phosphated derivatives of pyrridoxine, due to cost and availability issues. I do take B6 regularly, however.
> A non-time released megadose of B complexes will probably end up having most of it flushed out of the system, right?
I wouldn't go so far as to say "most". Or, perhaps I should say that, ultimately, both timed release and regular B-complex supplements contribute to nutrient rich urine. It's just that the shape of the curve, the blood concentration spike, is a little more rounded in the time-release scenario (which is better.... but substantially better, I don't know).
One way of viewing the body is to consider it as a set of 17 adjoining compartments (some are organs, like the liver, whereas others might be muscle, or bone), separated by membranes which control diffusion between the compartments. Upon being absorbed by the body, nutrients enter the blood compartment. The moment the blood is enriched in a nutrient is the moment that the other compartments get a chance to take some up across their membranes. Meanwhile, the kidneys are doing their thing, and dumping dissolved stuff into urine from the blood that passes by their membranes. (The bright yellow stain in urine from B-complex is B2, while other B's are not pigmented.) The fact that you see the vitamins in urine is evidence that all the body's compartments are truly having access to the nutrients, as the common element is the presence in the blood. That's just what happens to water-soluble vitamins. The same goes for vitamin C.
Lar
poster:Larry Hoover
thread:247722
URL: http://www.dr-bob.org/babble/20030802/msgs/248720.html