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Re: How was your first day on Depakote? » Jonathan

Posted by katia on July 26, 2003, at 13:34:21

In reply to How was your first day on Depakote? » katia, posted by Jonathan on July 25, 2003, at 23:54:54

Thanks for your long response!

I've got a couple of questions for you -
What is your diagnosis? And why are you adding Depakote onto lithium. Does lithium not do the trick for you?

Also, have you had any experiences where a mood stabiliser is enough for depression? My pdoc seems to want me off ADs (I am now) and onto only a mood stabiliser. I'm just worried that my depressions will get worse without some offset of the "mania".

Also, why do you (your pdoc) choose a tricyclic? Do the newer ones not work for you?
thanks again.
Katia

As well as 1000 mg of Depakote in two 500 mg doses, I'm continuing (at the same dose as before) the two meds that I was already taking:
(1) lithium carbonate 1000 mg every night, which I've been taking for six months, and
(2) lofepramine 70 mg three times a day, which I've been taking for a year.
Lofepramine is a tricyclic antidepressant with similar properties to desipramine (which it has superseded here in the UK) - inhibits reuptake of norepinephrine but not serotonin; antagonist at alpha-1 noradrenoceptors and 5-HT2 - it's rapidly metabolized into desipramine itself.


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