Posted by Larry Hoover on May 25, 2003, at 9:02:38
In reply to Re: Help needed. what is microM concentration » Larry Hoover, posted by rod on May 25, 2003, at 8:04:22
> > microM stands for microMolar (M = moles/litre),
>
> thanks, thats exactlay what I wanted to know.Sorry about the other details....too much information. It wouldn't mean much to anyone who doesn't use those concepts routinely.
> > Few drugs (none?)would reach microM concentrations under normal therapeutic use, as far as I know.
> >
> > Lar
> >
>
> you are right, even 300mg amitrip. is far away from this, if my calculation is right.
>
> thanks again
> RolandYou're welcome. I looked at venlafaxine (Effexor), just to check my conclusion against available data, and the peak blood concentration doesn't hit 1 microM. I can't see how a compartment which draws from the blood (i.e. the CNS) could possibly obtain *higher* concentrations.
Lar
poster:Larry Hoover
thread:228824
URL: http://www.dr-bob.org/babble/20030525/msgs/229006.html