Posted by Caleb462 on May 21, 2003, at 22:31:48
In reply to Mirapex » Ame Sans Vie, posted by Jack Smith on May 21, 2003, at 18:40:08
> > This medication has made my life so full of love, laughter, and just... well... complete. Even with an SSRI and benzodiazepine, I feel so human. And the depression? Gone with the wind. I just had to repeat it again--try it! You won't regret it!!!
>
> Congratulations!!! I am curious what dose you are at? What sort of side effects you have experienced as well? Also, do you, or anyone know, of long term side effects of dopamine agonists. I am just a little worried about movement disorders but I admittedly do not know much about this stuff just that, I think, dopamine depletion can cause them.It isn't dopamine delpetion per se that causes movement disorders. It's actually death of dopamine-containing neurons, or perhaps death of receptors?. I'm really not quite clear on it. A dopamine agonist shouldn't cause these problems, though, because it would likely cause upregulation of receptors - which would be considered a good thing. For instance, tobacco smokers have a much lower chance of developing alzheimers disease. This is because they are ingesting a nicotinic chollinergic agonist, and nicotinic chollinergic receptors upregulate in the prescence of large amounts of nicotine over a period of time. The more chollinergic receptors present, the less the prescence of alzheimers disease.
I mean... dopamine agonists are used to TREAT movement disorders, so it's safe to assume they are not going to cause a movement disorder. It's the antagonists you have to watch out for.
poster:Caleb462
thread:228132
URL: http://www.dr-bob.org/babble/20030520/msgs/228243.html