Posted by Ilene on January 22, 2003, at 9:56:11
In reply to Does Prozac 20mg + Remeron 45mg= 5-HT Syndrome? , posted by 3 Beer Effect on January 21, 2003, at 20:18:38
> I currently take Paxil CR 50 mg + Wellbutrin SR 300 mg. I haven't had any real side effects but the Paxil CR doesn't seem to improve my mood. I am always lethargic, anhedonic, melancholic etc.
>
> The best AD I ever took was Zoloft but after a month at 100 mg I started to get ridiculous insomnia which turned into my first 'manic' episode= ended up with a DUI from Xanax + Benadryl (no alcohol) that I took in order to go to sleep.
>
> I don't know if i'm Bipolar II or not- ADD kids often have odd, impulsive, hyper & manic-like reactions to Zoloft & Prozac. But I guess since both Paxil CR, Celexa didn't work for my depression that the only ADs that are going to help me are the "stimulating" SSRIs Prozac & Zoloft. (Wellbutrin & Effexor XR don't seem to help).
>
> Anyways my main question is will taking the combination of 20 mg of Prozac in the morning, & either 45 or 60 mg of Remeron at bedtime cause the dreaded Serotonin Syndrome?
>
> Thanks,
> 3 Beers....I think it depends on your particular sensitivities. I had symptoms resembling serotonin syndrome on Wellbutrin & Effexor XR. I felt better once I started tapering off the Effexor. (I still got hit with massive withdrawal about 36 hours after the last dose.)
I think if you titrate up the Remeron very slowly you may be able to stop if or when you start feeling strange. I can't really recall all my symptoms. I think they were dizziness, palpitations, headache. Uncomfortable but not emergency room awful.
On the other hand Prozac has such a long half-life that it stays in your system for something like 9 days. Maybe you can find out how long it takes to metabolize Remeron before you make your decision.
BTW, prozac was the 2nd AD I took. It worked--for a while. It triggered psychosis in someone I know thru the internet. I don't have warm and fuzzy feelings toward it anymore. YMMD
poster:Ilene
thread:136953
URL: http://www.dr-bob.org/babble/20030119/msgs/137032.html