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SSRIs vs TCAs

Posted by BrittPark on December 29, 2002, at 20:27:38

This is a curiousity post. I've taken imipramine (currently at 300mg/day) for about 20 years and besides dry mouth, which has made my dental bills big, I experience almost no side-effects, never have. At one point my psychiatrist added Paxil into my mix. It seemed to help for a while (I was experiencing a breakthrough depression at the time.) but made me nauseated and after 2-3 months extremely jittery. I discontinued the medication. So for me TCAs seem to have a much more benign side-effect profile than SSRIs.

I'd like to find out the conclusions of other people who have had experience with both TCAs and SSRIs.

My hidden motive is that I think that TCAs may have an unfair bad reputation for side-effects, and may be slightly more efficacious for people with melancholic depressions. There is a little research that supports the last claim.

So, please chime in.

Best wishes to all,

Britt


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poster:BrittPark thread:133725
URL: http://www.dr-bob.org/babble/20021223/msgs/133725.html