Posted by cybercafe on December 23, 2002, at 14:39:01
In reply to Re: do anti-psychotics make ADD worse?? » cybercafe, posted by Ritch on December 23, 2002, at 9:26:42
i'll give you a full reply later mitch, but for now i should let you know that while taking zyprexa/clonazepam i was able to achieve a "sense of wellbeing" by drinking 2 litres of pepsi
> > >
> > > They make stimulants less effective. If you are taking enough of an AP, your D2 receptors are all pretty much going to be blocked and a stimulant would likely have little effect. They can make ADD symptoms worse, too. I remember when I was trying low-dose Seroquel at bedtime, I would have a rebound super-attentive effect about 16 hrs. post-dosing, when the D2 receptors were becoming unoccupied.
> > >
> >
> > damn... actually i was reading an article on the journal of clinical psychiatry that implicated D4 receptors ...
> >
> > and apparently olanzapine binds strongly to D4 receptors
> >
> > but then i thought norepenephrine was also important in
> > ADD....
> >
> > what is the mechanism of action of ritalin, just
> > inhibition on the dopamine re uptake transporter?
>
>
> Ritalin also blocks the NE reuptake pumps and releases NE as well. Do you think your pdoc would be willing to reduce the olanzapine a bit? It almost sounds like your DA receptors generally are fully occupied, and there just isn't any wiggle room to activate them.
poster:cybercafe
thread:132899
URL: http://www.dr-bob.org/babble/20021223/msgs/133004.html