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Re: norepinephrine uptake inhibitors (help please!) » SLS

Posted by Ritch on October 11, 2002, at 9:39:28

In reply to Re: norepinephrine uptake inhibitors (help please!) » Ritch, posted by SLS on October 10, 2002, at 23:04:26

>
> > However, now I wonder how atomoxetine and bupropion stackup with regard to ADHD efficacy. The only thing that gripes me about bupropion is the active metabolites long half-life (up to 30hrs) which causes insomnia problems.--Mitch
>
>
> Hi Mitch.
>
> Have you considered trying Effexor (venlafaxine)?
>
> I recall seeing several studies showing it to be effective for ADHD. However, I don't recall if it was as effective for attentional features as it was for behavioral / mood features.
>
>
> Here's a Medline link. You might need to copy-and-paste the entire link that follows into your browser. Clicking might not work.
>
>
> ADHD and Effexor:
>
> http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=4&term=("attention+deficit"+OR+"adhd")+AND+venlafaxine&dispmax=200
>
>
>
> - Scott

Thanks for the link Scott. I am taking Effexor also, but only 12.5mg with WB in the morning. Effexor would work better if I could tolerate more of it. It seems that potent serotonin reuptake inhibitors tend to cause hypomania. I can't realize Effexor's advantages in the NE department unless I crank the dose way up-which I can't do. But, it is good for "task-switching" and great for anxiety. I wish there was another med (not a TCA), that was primarily an NE reuptake inhibitor, and also blocked the 5HT-transporter (but much less actively). I really wonder if just a 'pinch' of Reboxetine combined with a 'pinch' of Effexor would do the trick? I'm also taking Ritalin-LA 20mg in the afternoons, but it is uneven. I don't like stims much really-great for BP-depression, but they tend to make me too quiet and kind of "cold". Desipramine really made a difference, but I don't like the sleep-cycle disruption and anitcholinergic effects. It is like I can live in a fog and not be anxious, or I can clear the fog away but I am too uptight, it sucks. ---Mitch


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poster:Ritch thread:122549
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