Posted by MoBe on September 24, 2002, at 20:59:04
In reply to Re: only effective for depression at 15 or more mg, posted by djmmm on February 4, 2002, at 1:52:34
> > Some people break the 15 mg pills in half to use as a sleeping pill (7.5 mg), but the only effective doses for depression are 15-60 mg/day (the higher the dose the less the sedation).
> > Taking less than 15 mg means the Remeron is basically only working as a strong anti-histamine (sleeping pill) without any anti-depressant effects.
> >
> > If you are depressed why not take 15 mg or the 30 mg you were prescribed?- it will still help you sleep at 30 mg and will have a stronger anti-depressant effect.
>
> True....just take a higher dose, Remeron actually increases the release of serotonin and norepinephrine by blocking the alpha-2 auto receptors
>
> ... so, the higher dose will allow higher levels of norepinephrine to overpower the effects its antihistamine properties.I have some questions about using remeron
1)when you take the dose down, I know it increases the sedative effect but does it increase or decrease the tendency to be constipating.
2)When I take Benedryl, I get a paradoxical effect, ie. it doesn't make me sedated, it makes me hyper. Anyone have a theory on that?
3)Anyone getting myoclonus with remeron and how do they deal with it? I have tried magnesium (it worked a little), valerian (butthe pharmacists say that you shouldn't use valerian and antidepressents together. I find this curious considering valerian's safety record. Surely it has be safer than benzo's!!
Thanks
MoBe
poster:MoBe
thread:92754
URL: http://www.dr-bob.org/babble/20020922/msgs/120986.html