Posted by Shawn. T. on July 29, 2002, at 21:29:48
In reply to switch from venlafaxine to mirtazapine in Bipolar , posted by swingsnroundabouts on July 29, 2002, at 8:25:16
The venlafaxine should definitely have been tapered down. Some people have warned about mixing it with mirtazapine (Remeron), so I don't know if I want to suggest that. You might see about getting some Prozac (which have a very long half life) to help withdraw from the Effexor. I doubt that the mirtazapine is going to create the level of serotonin availability in your synapses that your brain was accustomed to. You should not experience a manic switch because mirtazapine blocks 5-HT2 receptors which are involved in bipolar II. If you do experience a switch, you will need to drop your dosage down to 15mg/day to decrease noradrenaline levels.
Shawn
poster:Shawn. T.
thread:114137
URL: http://www.dr-bob.org/babble/20020725/msgs/114252.html