Posted by Shawn. T. on July 15, 2002, at 2:53:45
In reply to Re: Do I need to call my pdoc immediately?, posted by cybercafe on July 15, 2002, at 1:21:28
I don't know where I need to be really. Not here, however. The Germans and Canadians seem to be really on top of all of this, but I like this country too much to leave it. I took my Remeron and slept for ten hours (that's how long I sleep if nothing wakes me up & I am sleeping properly). Interestingly enough, I woke up because of a vivid dream about being really thirsty. I was definitely in need of a drink after I rolled out of bed. By the way, I'm really uncomfortable suggesting any more prescription drugs; I absolutely have to know what effects they're having on various hormones and enzymes. It all keeps coming back to those hormones and enzymes. I really like how mRNA fits into this as well; good to know.
See
http://www.pulsus.com/CARDIOL/12_10/pras_ed.htm
for some information on superoxide dismutase (SOD), the antioxidant enzyme. I'm sure that you recall that DHEA increases the activity of platelet SOD.
See
http://www.mqrx.com/gateway/sod.html
and
http://www.mqrx.com/gateway/dhea.html
-I like those because they have direct links to medline in the text.Some great info on Alzheimer's Disease:
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=25833425
more on 7-alpha-hydroxylation at
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=15832347Nothing is purely good, and DHEA is included:
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=25411689There's a lesson on hepatocarcinogenesis at http://www.biochem.uwa.edu.au/TEACHING/3rd_Year/B352/Lectures/Hepatocarcinogenesis/sld001.htm
Maybe that L in LHPA axis should stand for liver. Seems as though cancer has a hormonal side. Keep your eyes off the naked rat. I'd like to think that this might help explain alcohol induced depression. Really shows how depression is not just a genetic thing. I've always been a fan of using environmental factors to explain certain things. Also, maybe ancients who emphasised the importance of bile may have been more intelligent than we once thought.See the following for some information on DHEA vs. DHEA-S
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=24277588Information on various DHEA derivatives
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=26683481
and
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=26252671On DHEA and women:
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=4562900The following is just a rough guide; it doesn't have references so buyer beware
http://www.mineralconnection.com/metabol.htmI like the idea for people taking anticholinergic drugs to take DMAE. Makes sense to me. I want some. Alpha Lipoic Acid is great! Low levels of pregnenolone would probably be higher due to an increase in the 17-hydroxylation or increased 3-beta-HSD activity on pregnenolone. I always keep this window open when reading about this stuff:
http://www.psychosomaticmedicine.org/content/vol61/issue5/images/large/G0465F1.jpegMore on lipoic acid
http://www.bodybuilding.com/store/ala.html
Sorry about the commercial nature of the site once again, but I'm sick of looking for some well done studies on it. Check out the books that that doctor has written. I know some of you itching to dump your antidepressants might like that. This too:
http://www.mercola.com/2001/aug/4/serotonin.htmI could sure help him explain why a "well" of serotonin might influence mood and bodily functions.
I'll end with this:
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=18682648Also some information on plasticity:
http://nootropics.com/neurogenesis/stemcell.htmlIf you're unaware of what we know about the dentate gyrus, see
http://www.fhs.mcmaster.ca/psychiatryneuroscience/research/research/researchday/Bruce_McEwen/keynote.htmlOne more thing about Modafanil. Anafranil is related, so I wonder if it has similar actions.
http://www.modafinil.com/modvamp.htmlBut how could I leave out information on serotonin? Can't let hormones steal all the glory.
http://www.biopsychiatry.com/sb-236057.htm
Blind faith in SSRI monotherapy is almost scary IMHO. You're all probably aware that my favorite antidepressants are Remeron and Wellbutrin, but I'm beginning to believe I may not need them. That Remeron sure does help me sleep though.
poster:Shawn. T.
thread:112274
URL: http://www.dr-bob.org/babble/20020709/msgs/112377.html