SSRI's, 5-HT supplement shown to increase cortisol

Posted by Shawn. T. on July 9, 2002, at 18:09:15

In reply to Remeron shown to reduce cortisol levels, posted by Shawn. T. on July 9, 2002, at 1:09:07

I think I can prove this even without using the study I referred to. Remeron (mirtazapine) blocks 5-HT2 receptors and therefore reduces cortisol levels. This action is shared by most atypical antipsychotics, and this may explain why some people benefit from combinations of atypicals and SSRI's. What I've found has important implications for the ineffectiveness of SSRI's and the dietary supplement 5-HT. The fish oil DHEA has been shown to lower cortisol levels by the way (the last link). I would therefore argue that DHEA is an effective antidote to certain SSRI side effects. I believe this is because DHEA is a precursor to androgens, which decrease cortisol.
On 5-HT2 antagonism and cortisol:
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=7178095
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=1054993
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=10831057
On adverse effects of cortisol:
http://www.psychosomaticmedicine.org/cgi/content/full/61/5/698
On paxil:
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=18838258
On DHEA:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=9264158&dopt=Abstract

Thread

Remeron shown to reduce cortisol levels Shawn. T. 7/9/02
SSRI's, 5-HT supplement shown to increase cortisol Shawn. T. 7/9/02
Re: SSRI's, 5-HT supplement shown to increase cortisol Doomed 7/10/02
Re: SSRI's, 5-HT supplement shown to increase cortisol katekite 7/10/02
Re: SSRI's, 5-HT supplement shown to increase cortisol Shawn. T. 7/11/02
me thinks cortisol is bad cybercafe 7/13/02
YES! Excellent link to a new magazine article Shawn. T. 7/13/02

Post a new follow-up

Notify the administrators

Start a new thread

poster:Shawn. T. thread:111825
URL: http://www.dr-bob.org/babble/20020709/msgs/111872.html