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Re: help -- serotonin-mediated flush? » medlib

Posted by katekite on April 12, 2002, at 9:19:41

In reply to Re: help -- serotonin-mediated flush?, posted by medlib on April 12, 2002, at 2:58:29

Hi,

Thanks for the information. I had read a list of tryptophan containing foods, and salmon was among them, but so were so many other things that I don't flush to, that I felt it would be wrong to assume it was due to tryptophan. Perhaps the combo of the fatty acids with tryptophan and my serotonergic benzodiazepine (klonopin). Or perhaps it is much higher in tryptophan than some of the other tryptophan containing foods.

One would think with all this serotonin available I would be euphoric. If only I could direct the flush more centrally. LOL.

I saw my psychiatrist yesterday (first time after buspar trial) and presented my serotonin theory and he reservedly agreed that it was likely, given my list of medication responses.

I find it extremely interesting that neurontin caused these side effects and wonder if it is a serotonergic drug. There have been sporadic reports of it having an antidepressant action and more pertinently perhaps a fairly common anti-anxiety effect and since these effects often indicate a serotonergic mechanism it makes me very curious. However, I simply have not seen this reported. What do you think, are you aware of any reports of serotonin involvement in the mechanism of neurontin action?

As far as ritalin goes, I took it last night around midnight when not able to go to sleep, and soon dropped off. I am more relaxed than I recall, and now need to taper down on klonopin a bit. I find it bizarre that I got to be 30, through grad school, without finding out this rather important information about myself.

The thinking with the short acting version is that since I'm so sensitive to all psychoactive drugs its worth seeing what length of effect I find for regular ritalin. It should also be quicker to find the effective dose, then I can translate that to a longer acting one. I'm considering asking to try dex etc as well, to see which fits me best. So far it seems to last 4-5 hrs, but I'm not at an optimal dose.

Anyhow, thanks for your comment and I'm curious what you have heard about neurontin and serotonin.

kate


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