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Re: Parnate advice anyone? Please! » Else

Posted by JahL on April 8, 2002, at 20:51:01

In reply to Parnate advice anyone? Please!, posted by Else on April 8, 2002, at 18:09:51

>I rarely hear about the more benign (but still annoying) side effects these drugs might produce. Would they be hard to tolerate for someone like me who gets agitated and angry on SSRIs and who suffers from muscle stiffness and insomnia on Wellbutrin and Effexor?

Parnate was a weird one for me. Usually I exceed the rec. max dose for ADs but I couldn't get past 25mg. Anything slightly above that & I would be out like a light, which I didn't expect b/c of the amph. metabolites you mention (just goes to show ymmv). I took 35mg once and couldn't be roused from la-la land for about 20hrs. At a lower dose it felt like an SSRI; irritability, DP etc.

I recently saw one of *the* top treatment resistant/BP guys in the UK. He was of the opinion that low dose Parnate + 3000mg of L-Tryptophan (Optimax) was one of the most effective combos available and it was his first-line recommendation for me. Didn't work out b/c I can't tolerate Optimax; became very irritable/hostile; like swallowing a bucketful of SSRIs.

Effexor was the worst ever for insomnia as well as everything else.

There are more positive stories than mine out there....

J.


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URL: http://www.dr-bob.org/babble/20020408/msgs/102447.html