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Re: Dopamine and MAO ?-- SLS

Posted by JohnX2 on March 28, 2002, at 16:11:26

In reply to Re: Do Lamictal Provigil counteract each other? » SLS, posted by JohnX2 on March 28, 2002, at 13:32:34


> I was looking into old schools blood pressure issue, and I found that dosing of bromocriptine *reduces* noradrenaline output for some people (and reduces blood pressure) by somehow indirectly reducing MAO. Food for thought. I should look into this some more, it sound like some interesting shit.
>

acutally the bromocriptine at the lower doses hits the presynaptic autorectors and lowers catecholinergic activity. One article suggested *increased* MAO activity.

Purportedly low dose of Pramipexole dose the same.

John

1: Kardiologiia 1991 Apr;31(4):22-4 Related Articles, Books, LinkOut


[Effects of bromocriptine on catecholamine metabolism in subjects with borderline arterial hypertension]

[Article in Russian]

Merkulova NK, Romaniuk SN, Petunin SN, Temirov AA.

Effects of bromocriptine on hemodynamics and catecholamine exchange were evaluated in patients with borderline arterial hypertension with respect to their family history. The agent was shown to be able to bring down blood pressure and decrease plasma catecholamine levels. With this, platelet monoamine oxidase activity was increased in persons with a family history of hypertensive disease.

PMID: 2067174 [PubMed - indexed for MEDLINE]


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