Posted by JohnX2 on March 6, 2002, at 4:40:16
In reply to Re: Moclobemide in atypical depression » JohnX2, posted by DINGBAT on March 4, 2002, at 5:33:14
Hi There,To be honest, the trends I've noticed on moclobemide don't look too good.
But one thing I've noticed is a lot of people (including me)
taking/taken the medicine in the 300-600 mg range did not fare well,
but I seem to see a lot of reports that it may be effective if the dose
is really pushed to 900+ mg.So I think you are in an interesting trade off position that I have
often looked at. Try a medicine with less hassle but fewer fame, or just go
the more proven route. I think one part of the answer is if you can pay
the price of doing a drug trial with a mediocre chance of success? Is the
reward for this (not having the crummy diet and finding a good medicine
maybe you could take for quite a while), going to offset the odds of a better
response and cheaper availability for Parnate? This is a question for
you to decide.Darn, I usually gamble on the low impact of "quality of life" and then
go for the stand-by's after failure, but that's just me. Sometimes you find
a med that allows you to have your cake and eat it to; Lamictal did that for me.Best wishes on your decision.
-John
> Hi JohnX2
>
> I am outside US - I am in South Africa. Wellbutrin is not yet available here.
>
> I've tried nearly everything and various 'cocktails'. Mostly they were ineffectual except for Efexor which was probably the most helpful at 300mg daily. I've never given the MAOI's a chance and I think they may have might have much to offer me. While Parnate is available here (and often the 'drug of choice' for atypical depression), I was thinking of trying moclobemide (brand name Aurorix here) to avoid 'crummy diet'. But other PB posts are encouraging re: "the diet" and it seems that it's not that bad IF you're getting a really good response. Most of my patients (I'm a psychologist) don't seem to have good responses to Aurorix at usual doses. Aurorix is also FAR more expensive than Parnate in South Africa. I have a good pdoc who it sufficiently humble to try any combo's with me. Do you think I should just take the Parnate leap? I could take Rivotril (you call it Klonopin) for any 'over-activation' or sleep problems.
poster:JohnX2
thread:95935
URL: http://www.dr-bob.org/babble/20020301/msgs/96667.html