Posted by christophrejmc on March 4, 2002, at 15:51:17
In reply to Re: MAOI-Bipolar » christophrejmc, posted by Jason911 on March 4, 2002, at 12:52:21
> Hey, you've got it backwards. Wellbutrin has been touted as being less likely to induce mania.
When did I say otherwise?
> My friend, people who are bipolar and go on MAOI's.. well it can be an absolute disaster. Where did you hear that MAOI's wouldn't produce mania in BP's??
Several sources. I can dig up references if needed... Wellbutrin and perhaps a few other newer antidepressants (and Lamictal) have taken their place, but it was once commonplace to use MAOIs (especially Parnate) to treat the depressive phase of bipolar depression.
> MAOI+BP = Mania potenital!!!
What do you base this on?
> Even though, I'd recommmend selegiline+phenylalanine.
I hope this combo works well for you, but you should know that selegiline+precursor loading hasn't been very well studied (and the studies that exist weren't large enough to prove much).
> You know the regimen I'd recommend. I'm sure you've read my other posts. And for those on Nardil and don't like it. Try 50mg selegiline daily. Should get same effect but no side-effects (maybe insomnia .. but hey there's always Klonopin!!)-Jason911
I'm pretty sure that high-dose selegiline has its fair share of side-effects; but you're right, they are most likely quite different than Nardil's. Incidentally, all MAOIs have some neuroprotective properties. I'm planning on trying selegiline next as I'm tired of Nardil's side-effects -- I'll start at MAO-B selective doses and I might try the PEA combo. I'll let you know how it goes.
-Chris
poster:christophrejmc
thread:96141
URL: http://www.dr-bob.org/babble/20020301/msgs/96357.html