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Re: Query: Serotonin syndrome...SSRI+MAOI interaction

Posted by Triss on February 26, 2002, at 22:55:02

In reply to Re: Query: Serotonin syndrome...SSRI+MAOI interaction, posted by bookgurl99 on February 25, 2002, at 11:11:24

> I just have a question bec. I'm new on Luvox;
> were you able to quit Luvox? I have been on it for a week and feel a 'crash' whenever it starts to wear off. Is this the sort of thing you experience, sort of a depression due to no more Luvox?
>
> I would just like to know as I am reconsidering using it.


I don't know whether or not the term, "crash", would describe it. What happened in my case was... in about three days after abruptly stopping the Luvox I found myself having difficulty sleeping, feeling more down about things than usual, and unable to relax, etc.
Following that, nausea began to develop and the above symptoms progressively got worse with each day. I became very restless and feeling like I desperately needed to go somewhere or do something, even though I had nowhere to go and no activity I did would bring relief. I could find no sense of peace.

Bear in mind that what I experienced, while occurring in response to (or being triggered by) my stopping Luvox (i.e. 200 mg/day stopped all at once), was not merely antidepressant withdrawal. It was (as diagnosed) major depression. Luvox itself is a very good antidepressant. It's just that in my case it didn't work for all my symptoms, prompting me to want to stop it and try something else, whereupon the withdrawal process triggered something horrible that usually just does not occur with most people who withdraw from Luvox.

Take care,
Triss


PS: And yes, I did successfully quit the Luvox. I'm now depression free (except for certain, long medication-resistant, residual symptoms) on 90 mg/day of Nardil.


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