Posted by JohnX2 on February 21, 2002, at 20:32:42
In reply to How does Buspar really work?, posted by Kristen on February 21, 2002, at 11:19:49
Hi,At the lower doses (30 mg or so), Buspar mainly
acts as a serotonergic modulator. It tends to slow down
the firing rate of hyperactive serotonin neurons. If
Your SSRI is making you agitated it can help in this
regard. So thus it may help your insomnia.At higher doses, buspar has a side metabolite that tends to
increase levels of dopamine and norepinephrine. This
usually kicks in more around 60 mg or so. This would help
to boost the anti-depressant effect. It may make you more
excitable, less depressed, help offset sexual dysfunction.
Might not be good for insomnia. Default disclaimer: everyone
reacts differently to medicines.Best regards,
John
> What a great board! I am Danish, so pardon my English. Tanks for answering my other question, I think I drop the Celexa-Buspar-Serzone combo indeed! My problem is panic and depression.
>
> But I have started to add some Buspar to 20 mg. Celexa because I felt so “blah” on 40 mg. Celexa alone. I feel much better, more energy, good mood and no change in anxiety levels! Some questions for you:
>
>
> How is Buspar really working? I thought I read in an earlier post that adding Buspar to SSRI will boost dopamine and NE?
>
> I had some problems with insomnia on Celexa alone, will this be better or worse when I add Buspar?
>
>
> Thanks, Kristen
poster:JohnX2
thread:94932
URL: http://www.dr-bob.org/babble/20020215/msgs/95045.html