Posted by Alan on November 27, 2001, at 15:26:30
In reply to Re: New Drug 4 Social Phobia. BPII. » JahL, posted by SLS on November 27, 2001, at 13:33:57
> >
> > > ************************************************
> > >
> > > Neurontin is an antiepileptic or antiseizure med, not an ssri.
> > >
> > > Alan.
> >
> > Who said it was an SSRI? And what's Neurontin got to do with all this?
> >
> > (a confused) J.
>
>
> Mitch's characterization of pregabalin is accurate.
>
> Pregabalin was developed as an anticonvulsant. Like gabapentin (Neurontin), it is structurally similar to the inhibitory "calming" neurotransmitter, GABA (Gamma-Amino-Butyric-Acid). However, neither drug seems to act like GABA in the brain. Both drugs appear to block certain kinds of calcium channels along the neuron. I'm sure they do other things as well.
>
> Among the therapeutic potentials that both Neurontin and pregabalin share are:
>
> 1. Anticonvulsant - seizures disorders
> 2. Anxiolytic - anxiety disorders
> 3. Antinociceptive - pain disorders
>
> I guess #2 is where social phobia fits in.
>
>
> - Scott**********************************************
Thanks Scott for clarifying. This is my understanding too.
Alan
poster:Alan
thread:85200
URL: http://www.dr-bob.org/babble/20011123/msgs/85319.html