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Re: The uses of Neurontin-PaulB

Posted by PaulB on July 29, 2001, at 12:28:51

In reply to Re: The uses of Neurontin-PaulB, posted by MM on July 19, 2001, at 0:01:06

> Can you tell me more about Pregabalin? Will It be approved any time soon? Can it be used as a mood stabilizer?

Pregabalin is very similar to gabapentin but more potent. Pfizer, the drug company that is developing it has restricted the use of it at this time for certain patients because there was an increased incidence of some type of tumor in mice when given the drug for a life-time. At this stage Im not sure what the significance of this is but it doesnt seem to be a major set-back and Pfizer may still be going ahead to submit Pregabalin for FDA approval this Autumn as originally planned. They hope they can get licence for its use in neuropathic pain, epilepsy first and then a variety of anxiety disorders where it has shown much promise(Generalised Anxiety Disorder,Social Phobia, Panic Disorder)
Its expected to be a big earner for Pfizer.


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