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Re: Thorazine and brain damage » MB

Posted by Elizabeth on July 18, 2001, at 20:26:49

In reply to Re: Thorazine and brain damage » Else, posted by MB on July 18, 2001, at 14:45:14

> I wish there was a way to block the antihistaminic action of these psychotropic drugs.

Some are more antihistaminic than others. Haldol, Stelazine, and Moban are some of the less sedating antipsychotics. Desipramine is the least antihistaminic of the tricyclic antidepressants (although protriptyline is probably more activating).

> Remeron would have been perfect for me if it hadn't have been for the antihistamine sedation.

How much Remeron were you on.

> I guess an H-1 agonist (to counteract the H-1 blocking action of these drugs) would make a person miserable. Wouldn't it cause allergic-type reactions?

Yes, that's one thing histamine does. Opioids, for example, cause histamine release (to varying degrees) which is why a lot of people get itchy on them. Promethazine, diphenhydramine, doxepin, and other antihistamines can be used to prevent the itching.

> parenthetically, can you believe my doctor switched me to Remeron when I told him Paxil was making me too tired and that I was gaining weight? Do these guys even listen?

I take it your question is a rhetorical one. < g >

-elizabeth


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poster:Elizabeth thread:69927
URL: http://www.dr-bob.org/babble/20010714/msgs/70726.html