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Re: Remeron - less sedation at higher dose?

Posted by Lupercal on July 6, 2001, at 3:29:17

In reply to Re: Remeron - less sedation at higher dose? » Lupercal, posted by Elizabeth on July 6, 2001, at 0:22:31

> > > Clomipramine?
> >
> > Not familiar with that one. Brand name (probably be different here anyway)
>
> Anafranil. (It's a tricyclic with more effect on serotonin than most tricyclics.)

Oh, ok. I have some of that here. It was prescribed for me once, but I never took it, after finding it on a list of ototoxic drugs (drugs which can actually cause hearing damage)


> I meant, why would Prozac trigger tinnitus?

Don't ask me, I'm a double English major ;)

> > Prior to that it had only ever been a slight nuisance. A couple of days after taking prozac it went ballistic and stayed there.
>
> Ahh -- so it was there before the SSRIs, but they exacerbated it. Any idea why they would do that?

Again, nope - except that SSRI's are known to temporarily worsen tinnitus in the first few weeks for some people. However Dr Stuart Shipko, who has a panic disorder clinic in ca, has been interviewed stating that tinnitus suferes should stay away from SSRI's because he's seen cases of intractible tinnitus atfer SSRI use.


> > >Did you talk to a GP about it?
> >
> > It seems like I do little else sometimes.
>
> And you haven't gotten any answers or suggestions? Do you know anything about how tinnitus is treated in general? That's where I'd start out. I've heard of antihistamines such as hydroxyzine and promethazine being used, but I'd imagine there are other, less sedating options.

I think I've been through everything there is to try with tinnitus.

> > > > Luvox in particular had a magic bullet effect, improving my mood substantially within 8 hours!
> > >

> > The first time I took Luvox it hit me the same night (the second time I took Luvox I got serotonin syndrome, so that wasn't exactly a fair trial).
>
> Really? What symptoms did you have?

Anxiety, derealization, cold sweats, I can't remember too much about it. The only thing different from the first time I took luvox is that, the second time, I'd come off pamelor about 2 weeks earlier - which ought to have been enough time, but it seems I am just ultra-sensitive to serotonergic drugs.

> I'm not sure what "new breed of SSRIs" you're talking about. SSRIs increase the available amount of serotonin, which acts as an agonist at all serotonin receptors (by definition < g >). Can you tell me anything more about the drugs you're thinking of?

No, I'm sorry. I'm only going on the fact my pharmacist explained to me that these new SSRI's were coming soon, and that they have the properties I outlined above. If they're coming soon in Australia, chances are they're already available in the USA.

Tim


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poster:Lupercal thread:68802
URL: http://www.dr-bob.org/babble/20010701/msgs/69153.html