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Re: interactions between AD's and natural herbs

Posted by SalArmy4me on June 26, 2001, at 9:54:38

In reply to interactions between AD's and natural herbs , posted by asoiferman on June 26, 2001, at 8:56:50

Psychosomatics. Volume 61(5) September/October 1999 p 712 Dietary Supplements and Natural Products as Psychotherapeutic Agents
[Special Issue: Psychopharmacology And Psychosomatic Research]
Fugh-Berman, Adriane MD; Cott, Jerry M. PhD:

Adverse Effects and Interactions.
Ginseng can cause estrogenic effects even though it does not actually contain phytoestrogens. Two cases of postmenopausal uterine bleeding have been reported. One occurred in a patient who ingested a geriatric formula containing ginseng (86); another occurred in a 44-year-old postmenopausal woman after use of a face cream that contained ginseng (87). Follicle-stimulating hormone levels rose to normal postmenopausal levels after use of the face cream was discontinued. Three weeks after rechallenge, the level of follicle-stimulating hormone dropped from 70 to 27 mIU; 1 week later another episode of uterine bleeding occurred. One case of swollen breasts and diffuse nodularity was reported in a 70-year-old woman (88). The symptoms disappeared on discontinuation of the ginseng and recurred on rechallenge. Another report of five cases of mastalgia lacks detail and thus is unevaluable (89).

Two cases of possible interactions between ginseng and phenelzine (Nardil) have been described. In the first case, a 64-year-old woman developed headache and tremor after consuming the two together (90); in the second case, a 42-year-old woman with a history of unipolar depression experienced what seemed to be a manic reaction to the combination of ginseng and bee pollen with phenelzine (91). In neither case was the ginseng preparation analyzed to ensure that ginseng was actually present. A number of purported ginseng products contain no ginseng and may contain other herbs, such as ephedra (92).


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