Posted by Sunnely on June 20, 2001, at 0:33:37
In reply to Celexa and no energy, headache, yawning, posted by Janelle on June 17, 2001, at 23:07:36
Hi Janelle,
As Bill said in the previous post, 3 weeks is not long enough for trial of an antidepressant. And, I tend to agree with him that may be 40 mg/day is more than what you need at this time. Could a lower dose alleviate these problems?
And the yawning. One hypothesis as to why selective serotonin reuptake inhibitors (SSRIs) such as Prozac, Zoloft, Paxil, Celexa cause yawning may be related to the effect of serotonin on dopamine. Serotonin have an indirect effect ont he dopamine system, particularly dopamine receptor 2 (D2). Yawning appears to be related to the action of this receptor.
Another hypothesis for the occurrence of yawning is the possible interaction between serotonin and the opiate systems. Yawning is a common clinical symptom of opiate withdrawal.
If the yawning is persistent and intolerable (or embarrassing), you may want to consider trial of cyproheptadine (Periactin), a serotonin antagonist. One potential problem, however, it may diminish the antidepressant action of Celexa. I know. It's always something.
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> 40 mg of Celexa going on 3 weeks, with a teeny lift in depression but no energy, foggy head, headache and yawning (plus no relief from anxiety). Should I have started to feel better and should the side effects have dissipated by now? Thanks.
poster:Sunnely
thread:66926
URL: http://www.dr-bob.org/babble/20010618/msgs/67159.html